Publications

Recent Publications

• Perianal Fistulizing Crohn’s Disease: Utilizing the TOpClass Classification in Clinical Practice to Provide Targeted Individualized Care
  • Luke N. Hanna, Sulak Anandabaskaran, Nusrat Iqbal, Jeroen Geldof, Jean-Frédéric LeBlanc, Anders Dige, Lilli Lundby, Séverine Vermeire, André D’Hoore, Bram Verstockt, Gabriele Bislenghi, Danny De Looze, Triana Lobaton, Dirk Van de Putte, Antonino Spinelli, Michele Carvello, Silvio Danese, Christianne J. Buskens, Krisztina Gecse, Roel Hompes, Marte Becker, Jarmila van der Bilt, Wilhelmus Bemelman, Shaji Sebastian, Gordan Moran, Amy L. Lightner, Serre-Yu Wong, Jean-Frédéric Colombel, Benjamin L. Cohen, Stefan Holubar, Nik S. Ding, Cori Behrenbruch, Kapil Sahnan, Ravi Misra, Phillip Lung, Ailsa Hart, Phil Tozer.
• Stem Cells and Stem Cell-Derived Factors for the Treatment of Inflammatory Bowel Disease with a Particular Focus on Perianal Fistulizing Disease: A Minireview on Future Perspectives
  • Amy L. Lightner, Peter M. Irving, Graham M. Lord, Aline Betancourt.
• Perianal Fistulizing Crohn’s Disease-Associated Anorectal and Fistula Cancers: Systematic Review and Expert Consensus
  • Serre-Yu Wong, Cathy Rowan, Elvira Diaz Brockmans, Cindy C.Y. Law, Elisabeth Giselbrecht, Celina Ang, Sergey Khaitov, David Sachar, Alexandros D. Polydorides, Leon Shin-Han Winata, Bram Verstockt, Antonino Spinelli, David T. Rubin, Parakkal Deepak Dermot P.B. McGovern, Benjamin D. McDonald, Phillip Lung, Lilli Lundby, Amy L. Lightner, Stefan D. Holubar, Luke Hanna, Carla Hamarth, Jeroen Geldof, Anders Dige, Benjamin L. Cohen, Michele Carvello, Cristiana Bonifacio, Gabriele Bislenghi, Corina Behrenbruch, David H. Ballard, Emre Altinmakas, Shaji Sebastian, Phil Tozer, Ailsa Hart, Jean-Frederic Colombel.
• A phase IB/IIA study of ex vivo expanded allogeneic bone marrow-derived mesenchymal stem cells for the treatment of rectovaginal fistulizing Crohn’s disease
  • Amy L. Lightner, Jane S. Reese, Justin Ream, Douglas Nachand, Neda Dadgar, Ashley Adams, Alexandra VanDenBossche, Ana Otero Pineiro, Tracy Hull.
• Bone Marrow Mesenchymal Stem Cell-Derived Extracellular Vesicle Infusion for the Treatment of Respiratory Failure From COVID-19: A Randomized, Placebo-Controlled Dosing Clinical Trial
  • Amy L. Lightner, Vikram Sengupta, Sascha Qian, John T. Ransom, Sam Suzuki, David J. Park, Timothy I. Melson, Brian P. Williams, James J. Walsh, Mustafa Awili.
• A Phase I Study of Ex Vivo Expanded Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells for the Treatment of Pediatric Perianal Fistulizing Crohn’s Disease
  • Amy L. Lightner, Ana Otero-Pineiro, Jane Reese, Justin Ream, Douglas Nachand, Ashley C. Adams, Alexandra VanDenBossche, Jacob A. Kurowski.
• A Phase IB/IIA Study of Ex Vivo Expanded Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells for the Treatment of Perianal Fistulizing Crohn’s Disease
  • Amy L. Lightner, Jane Reese, Justin Ream, Douglas Nachand, Xue Jia, Neda Dadgar, Scott R. Steele, Tracy Hull.
• Durable Response in Patients With Refractory Fistulizing Perianal Crohn’s Disease Using Autologous Mesenchymal Stem Cells on a Dissolvable Matrix: Results from the Phase I Stem Cell on Matrix Plug Trial
  • Eric J. Dozois, Amy L. Lightner, Allan B. Dietz, Joel G. Fletcher, Yong S. Lee, Jessica J. Friton, William A. Faubion.
• A Phase IB/IIA Study of Allogeneic, Bone Marrow-derived, Mesenchymal Stem Cells for the Treatment of Refractory Ileal-anal Anastomosis and Peripouch Fistulas in the Setting of Crohn’s Disease of the Pouch
  • Amy L. Lightner, Jane Reese, Justin Ream, Douglas Nachand, Xue Jia, Ana Otero Pineiro, Neda Dadgar, Scott Steele, Tracy Hull.
• A phase IB/IIA study of remestemcel-L, an allogeneic bone marrow-derived mesenchymal stem cell product, for the treatment of medically refractory ulcerative colitis: an interim analysis
  • Amy L. Lightner, Neda Dadgar, Caroline Matyas, Kavita Elliott, Clifton Fulmer, Neha Khaitan, Justin Ream, Douglas Nachand, Scott R. Steele.
• Remestemcel-L allogeneic bone marrow-derived mesenchymal stem cell product to treat medically refractory Crohn’s colitis: preliminary phase IB/IIA study
  • Amy L. Lightner, Justin Ream, Douglas Nachand, Clifton Fulmer, Miguel Regueiro, Scott R. Steele.
• Surgical Management of Crohn’s Disease
  • Valery Vilchez, Amy L. Lightner.
• New insights on the surgical management of ulcerative colitis in the 21st century
  • Paulo G. Kotze, Lianne Heuthorst, Amy L. Lightner, Aderson O. M. C. Damião, Willem A. Bemelman.
• Classifying perianal fistulising Crohn’s disease: an expert consensus to guide decision-making in daily practice and clinical trials
  • Jeroen Geldof, Nusrat Iqbal, Jean-Frédéric LeBlanc, Sulak Anandabaskaran, Rachel Sawyer, Christianne Buskens, Willem Bemelman, Krisztina Gecse, Lilli Lundby, Amy L. Lightner, Silvio Danese, Antonino Spinelli, Michele Carvello, Omar Faiz, Janindra Warusavitarne, Phillip Lung, Danny De Looze, André D’Hoore, Séverine Vermeire, Ailsa Hart, Phil Tozer.
• Anorectal Strictures in Complex Perianal CD: How to Approach?
  • Amy L. Lightner, Miguel Regueiro.
• Postoperative outcomes after preoperative ustekinumab exposure in patients with Crohn’s disease: a systematic review and meta-analysis
  • Rajat Garg, Babu P. Mohan, Suresh Ponnada, Miguel Regueiro, Amy L. Lightner, Benjamin Click.
• Getting the most out of MRI in perianal fistula: update on surgical techniques and radiological features that define surgical options
  • N. Iqbal, P. J. Tozer, J. Fletcher, A. L. Lightner, C. Sackitey, A. Corr, U. Patel, R. Ilangovan, P. Lung.
• Ileal pouch-anal anastomosis in the elderly: A systematic review and meta-analysis
  • Karina E. Pedersen, Xue Jia, Stefan D. Holubar, Scott R. Steele, Amy L. Lightner.
• IPAA in Known Preoperative Crohn’s Disease: A Systematic Review
  • Amy L. Lightner, Xue Jia, Karen Zaghiyan, Phillip R. Fleshner.